Winner by a Hair
Both products offer a number of solid features, and both come with few weaknesses, mostly surrounding standard administration functionality, as well as schema-change management and data import/export functionality. Those weaknesses are a fairly big deal in my world, but they aren't showstoppers. Personally,because of those weaknesses,I don't imagine either tool becoming a one-stop replacement for the tools I already use. However, both DBArtisan and Quest Central offer powerful functionality that I wouldn't hesitate to acquire for supplemental needs in the right environments.
I've been both a reluctant DBA and a seasoned veteran, and I can say that I'd be comfortable using either of these tools or recommending them to colleagues. Both provide value in terms of making management easier, and both offer valuable services that help ensure better uptime, scalability, and reliability—but DBArtisan takes a slight edge thanks to its strong object editors.
See Table 1